CTC Research GmbH ()

CTC Research GmbH is specialized in automated high-throughput cell detection and cell classification based on imaging methods. Involving artificial intelligence, we are able to detect smallest shape features of cells indicating anemia or blood cell related diseases such as malaria. Our latest scope of research comprises a filtration and detection device to isolate circulating tumor cells from whole blood.

Role and Commitment of key persons (including supervisors)

Dr. Stephan Quint, CTO, 50%, Konrad Hinkelmann, Senior programmer, 45%, Constantin Schwaab, CEO, 5%

Key Research Facilities, Infrastructure and Equipment

CTC research is highly expertized in low and high level programming and implementation of imaging processing and evaluation algorithms on a variety of computational platforms. Besides standard 2D imaging, we developed toolboxes to effectively process 3D images of cells e.g. obtained from confocal microscopes. Using industrial standards such as OpenCV and CUDA (NVIDIA), we aim to implement highly parallelized processing structures to achieve optimal performance. Our infrastructure and equipment mainly consists of computational resources such as high performance computers. We provide a laboratory with standard equipment for liquid handling as well as a microscopic setup to evaluate filters and to test automated imaging routines.

Status of Research Premises

CTC research is a fully private SME. Our office and laboratory is rented in a shared office building. Our research premises are fully independent.

Relevant Publications and/ or Research/ Innovation Product

• Kihm A., Kaestner L., Wagner C., Quint S. (2018) Classification of red blood cell shapes in flow using outlier tolerant machine learning. PLoS Comput Biol 14(6): e1006278. • Quint S., Christ A.F., Guckenberger A., Himbert S., Kaestner L., Gekle S., et al. 3D tomography of cells in micro-channels. Applied Physics Letters. 2017;111(10):103701. • Quint S., inventor; CTC Research GmbH, assignee. Filter for blood filtration and filtration device. Luxembourg patent LU100992 (pending). 2018 Aug. 8.